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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2178 Results for "
Garcinia xanthochymus Hook. f. ex T. Anders.
" in MedChemExpress (MCE) Product Catalog:
Products (2178)
2178 Results for "Garcinia xanthochymus Hook. f. ex T. Anders." in MCE Product Catalog:
164
164 Publications Verification
Synonyms: Adenosine 5'-triphosphate disodium salt, 100 mM Solution, PCR Grade
58
58 Cited Publications
MRTX1133 is a noncovalent, potent, and selective alkyne-based KRAS G12D inhibitor. MRTX1133 optimally fills the switch II pocket and extends three substituents to favorably interact with the protein, resulting in an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 prevents SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex, thereby inhibiting mutant KRAS-dependent signal transduction. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells. MRTX1133 has single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor models harboring KRAS G12D mutations .
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Category:
Disease Research Antibacterial Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields
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Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
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Category:
Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields
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N-Nitroso-N-methylurea (NMU;MNU;NMH) is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of diazomethane .
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13 Cited Publications
Cat. No.: HY-W016319
CAS No.: 138-15-8
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12
12 Cited Publications
Synonyms: MC-207,110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride
9
9 Cited Publications
Cat. No.: HY-N0473A
CAS No.: 69847-45-6
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8
8 Cited Publications
SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation .
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7 Cited Publications
Cat. No.: HY-W011391A
CAS No.: 7300-59-6
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7
7 Cited Publications
Cat. No.: HY-W345421
CAS No.: 122864-94-2
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6
Category:
Cardiovascular Disease Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Rubiaceae Plants Disease Research Fields Indole Alkaloids
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6
Category:
Natural Products Guttiferae Plants Garcinia hanburyi Hook. f. Disease Research Fields Cancer
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5
5 Cited Publications
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5 Cited Publications
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5
5 Cited Publications
Cat. No.: HY-W009203
CAS No.: 30925-07-6
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5 Cited Publications
Cat. No.: HY-W142119
CAS No.: 2792-66-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
